Through the survey showed that obesity and the incidence of diabetes has a clear relationship, but also for type Ⅱ diabetes mellitus. Over 40 years of age in patients with type Ⅱ diabetes, the body weight is more than 10 percent more than the standard 2 / 3, also shows that closely related to obesity and diabetes. The majority of scholars believe that obesity is type Ⅱ diabetes, one of the important factors.
Obese people with diabetes easy to do why? Medical researchers think that with the fat cell membrane to reduce the number of insulin receptor and insulin receptor for insulin-related factors such as affinity decreased. Normal fat cell membrane insulin receptor density per square micron of about 10 receptors, each of fat cells there are about more than 10,000 receptor. Obese fat mast cell membrane to reduce the density of the insulin receptor, a decrease in the number, affinity and insulin decreased, study shows obese type Ⅱ diabetes mellitus, erythrocyte insulin receptor and the affinity is only half the normal plasma insulin concentrations high but lower than normal small effect of sugar. Prove that there is a study under the same conditions, obese glucose consumption rate was only 40% of the control group, obese body that is not sensitive to insulin so glucose utilization decreased. Since the body is not sensitive to insulin, therefore increasing the demand for insulin, islet p cells must secrete more insulin to meet the needs of the body to control blood sugar in normal range. In order to meet this need, the long-term islet cells eventually lead to the overload of work 9 islet cell failure and diabetes.
Obesity on insulin sensitivity can be changed, the key is to control diet, excessive intake of food is often one of the reasons for obesity. Seriously as long as the obese control diet, the best high-fiber foods and appropriate physical exercise to strengthen, will be able to reduce obesity, reduce the hypertrophy of fat cells, their number and affinity of receptor to recover, so that the restoration of the body sensitive to insulin sex, this will help control the symptoms of diabetes so that blood sugar back to normal.
3. Diabetes, especially Type I diabetes is not only the serum antibody against insulin-secreting cells but also of many anti-self-organ-specific antibodies, antibodies such as anti-thyroid cells 2-4 times the normal, anti-adrenal antibodies in normal people
Group rare, and in patients with diabetes, about 30 times in non-diabetics.
4. Diabetes is often accompanied by patients or their relatives have other autoimmune diseases, such as: diffuse goiter with hyperthyroidism, chronic lymphocytic thyroiditis, primary hypothyroidism, primary adrenocortical function decline (Ah-sen's disease shovel ), myasthenia gravis, pernicious anemia, which are related to autoimmune diseases of the.
In short, the above study shows the incidence of diabetes and auto-immune, but the immune response caused by the initiating factors and the relationship between genetic factors and have yet to be further clarified.
April 19, 2009
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