What are the predisposing factor of diabetes?

Diabetes-induced factors are: infection, obesity, reduced physical activity, pregnancy and environmental factors.

1, infection

Infection in the pathogenesis of diabetes account for a very important incentive for the location, especially in HIV type Ⅰ diabetes mellitus is a major predisposing factor. In animal studies found that many viruses can cause inflammation and pathogenicity islet, including encephalitis virus. Myocarditis virus, Coxsackie B4 virus. Virus infection can cause pancreatic inflammation, leading to inadequate insulin secretion resulting from diabetes. In addition, the virus can make the potential increase of diabetes mellitus to become overt.

2, obesity

The majority of patients with type Ⅰ diabetes mellitus type obesity. Obesity is another factor-induced diabetes. When obese fat and muscle cell membrane cell membrane insulin receptor decrease in the number of pro-insulin and lower the ability of cells decreased sensitivity to insulin, resulting in the use of sugar obstacles to the emergence of hyperglycemia and diabetes
Disease.

3, physical activity

China's farmers and miners, the incidence of diabetes was significantly lower than that of urban residents, urban population that may be related to participation in physical activity less relevant. Increased physical activity can reduce or prevent obesity, thereby increasing insulin sensitivity, so that glucose can be used there without diabetes. In contrast, if the reduction in physical activity, they easily lead to obesity, and reduce tissue sensitivity to insulin, glucose utilization disruption can lead to diabetes.

4, pregnancy

During pregnancy, increased estrogen, estrogen can induce autoimmunity, resulting in destruction of islet β-cells, on the other hand, estrogen and the role of insulin confrontation, so many pregnancy-induced diabetes can be.

5, environmental factors

The basis of genetic and environmental factors in diabetes as an incentive occupy very important position. Environmental factors include: air pollution, noise, social competition and so on, these factors induced mutation, mutant gene with the severity of the above factors and duration of growth and more and more, up to a certain degree of mutation (ie, medical known as the "threshold") that the occurrence of diabetes.